Visualizing the dynamic human genome with DHO 3D tracking and Light Sheet Microscopy

Visualizing the dynamic human genome with DHO 3D tracking and Light Sheet MicroscopyVisualizing the dynamic human genome with DHO 3D tracking and Light Sheet Microscopy

Using a DHO double-helix phase mask combined with light sheet microscopy, the Gustavsson Lab at Rice University has developed a new way to monitor chromatin throughout the entire nucleus over long time scales, revolutionizing our ability to understand its dynamics and changes in response to disease.