SPINDLE²™

SPINDLE²™

Dual-channel 3D imaging module

SPINDLE² is the ultimate solution for achieving multichannel single-shot 3D imaging with your existing microscope.

Offering two simultaneously imaged, individually adaptable channels, SPINDLE² adds multicolor, multimodal, depth-tunable imaging capabilities with endless potential.

  • Instantaneously upgrade your 2D microscope into an advanced 3D nanoscale imaging system with simultaneous multichannel capture using a single camera
  • Features a compact form factor, interchangeable DHO phase masks, and tight integration with 3DTRAX image processing and analysis software
  • Suitable for a broad range of 3D life sciences and inspection applications - use with any DHO phase mask
  • Mix and match imaging modalities between channels
  • Unlock vast imaging potential with the sample preparation and illumination method of your choice
  • Leverage bypass mode to perform single-channel experiments or collect 2D images
  • Compatible with most scientific optical microscopes and cameras

Use SPINDLE²® for

3D SMLM
3D particle tracking
Volumetric imaging
STORM
PALM
PAINT
Light sheet
HILO
TIRF
Widefield
CLEM
FRET & smFRET
FISH & smFISH
Simultaneous multicolor
Polarization imaging
Brightfield
Darkfield
Inspection
3D surface metrology
Spatial omics

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3DTRAX® in action

3D SMLM

3D SMLM

Reconstruct entire 3D structures with molecular precision

Deep Focus smFISH

Deep Focus smFISH

See entire structures in focus with 5x fewer axial slices

4D live-cell tracking

4D live-cell tracking

Capture time evolution of molecular targets in 3D

Spatial omics counting

Spatial omics counting

Rapidly & accurately count labeled molecules through a 3D volume

3DTRAX® modules

3D super resolution

Turn raw images into super-resolved 3D point clouds

3D PSF localization
Drift correction
Accurate photon counting
Cluster analysis

4D particle tracking

Track motion of particles in dynamic systems over time & space

3D PSF localization
Track segmentation
Accurate photon counting
Drift correction

2.5D particle counting

Accurately count high-spatial-density labeled molecular targets

3D PSF localization
Accurate photon counting
Drift correction
Cluster analysis

Deep Focus deconvolution

Enhance resolution & contrast of extended-depth images

Enhance resolution
Increase contrast
Reconstruct 3D volume from efficient axial sampling
Use GPU for accelerated performance

Data visualization and export available for all modules

3DTRAX.AI™

Upgrade to 3DTRAX.AI to use our top-performing Al models

3DTRAX.AI offers across-the-board improvements in:

PSF localization speed
PSF localization yield
PSF localization accuracy
Low-signal PSF localization
High-spatial-density PSF localization